Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770213 | 0.89 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27995196 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27692878 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27692877 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27826211 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27994977 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL28104012 | 0.86 | TSHR (0.43) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27520150 | 0.85 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL27776361 | 0.77 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL29028281 | 0.76 | ADRA1A (0.38) | TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100510037-C | Friction regulator for lubricating oil and lubricating oil composition | SANYO CHEMICAL IND LTD (JP) | 2009-07-08 | — | — | CN | disclosed |
| CN-1643119-A | Friction modifier for lubricating oil and lubricating oil composition | SANYO CHEMICAL IND LTD (JP) | 2005-07-20 | — | — | CN | disclosed |