SCHEMBL2759752

SCHEMBL2759752

CCC(=O)OC1=C(c2cc(C)ccc2C)C(=O)NC12CCN(OC)CC2

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACACB O00763 11/20 0.38
ACACA Q13085 11/20 0.38
THRB P10828 1/20 0.33
ACHE P22303 2/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
MDM2 Q00987 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251850 0.90 ACACB (0.38) ACACBACACATHRBKMT2AMEN1
SCHEMBL29836257 0.90 ACACB (0.38) ACACBACACATHRBKMT2AMEN1
SCHEMBL16581663 0.89 ACACB (0.40) ACACBACACATHRBKMT2AMEN1
SCHEMBL2759751 0.89 ACACB (0.38) ACACBACACATHRBKMT2AMEN1
SCHEMBL30204267 0.89 ACACB (0.40) ACACBACACATHRBKMT2AMEN1
SCHEMBL248519 0.88 ACACB (0.37) ACACBACACATHRBKMT2AMEN1
SCHEMBL2759743 0.87 ACACB (0.36) ACACBACACATHRBACHEKMT2A
SCHEMBL2759745 0.87 ACACB (0.36) ACACBACACATHRBMDM2
SCHEMBL2759742 0.86 ACACB (0.36) ACACBACACATHRBKMT2A
SCHEMBL2759764 0.86 ACACB (0.36) ACACBACACATHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352375-B1 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2015-03-25 EP disclosed
US-8722578-B2 Spiroheterocyclic pyrrolidinedione herbicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2014-05-13 US disclosed
US-8722578-B2 Spiroheterocyclic pyrrolidinedione herbicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2014-05-13 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
US-20120004105-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2012-01-05 US disclosed
WO-2010052161-A2 HERBICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004105-A1 HERBICIDAL COMPOSITIONS DDT, CAT, HDHD5 ACACB 704/4885ACACA 1250/4885THRB 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.