Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.42 |
| ▸ | KDM6B | O15054 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30017867 | 0.82 | KDM4C (0.46) | MAPTTDP1KDM4CKDM6BKDM4E | |
| SCHEMBL29573953 | 0.79 | SLC22A12 (0.53) | TDP1CYP1A2CYP3A4CYP2D6KDM4C | |
| SCHEMBL22717569 | 0.79 | SLC22A12 (0.53) | TDP1CYP1A2CYP3A4CYP2D6KDM4C | |
| SCHEMBL5151553 | 0.79 | HDAC4 (0.59) | MAPTTDP1HDAC4HDAC2HDAC8 | |
| SCHEMBL31006674 | 0.78 | GPBAR1 (0.50) | KDM4C | |
| SCHEMBL115719 | 0.76 | KDM4C (0.53) | MAPTTDP1KDM4CKDM6BKDM4E | |
| SCHEMBL30578227 | 0.76 | KDM4C (0.53) | MAPTTDP1KDM4CKDM6BKDM4E | |
| SCHEMBL25153602 | 0.75 | SLC22A12 (0.47) | KDM4C | |
| SCHEMBL31019038 | 0.75 | SLC22A12 (0.47) | KDM4C | |
| SCHEMBL31006682 | 0.75 | GPBAR1 (0.47) | CYP1A2KDM4CKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100406441-C | Cyclic amine compounds | KOWA CO (JP) | 2008-07-30 | — | — | CN | disclosed |
| CN-1604893-A | Cyclic amine compound | KOWA CO (JP) | 2005-04-06 | — | — | CN | disclosed |