Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL556313 | 0.92 | DPP4 (0.51) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL27600217 | 0.89 | DPP4 (0.49) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL555556 | 0.89 | DPP4 (0.49) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL555408 | 0.84 | DPP4 (0.62) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL4073091 | 0.84 | DPP4 (0.62) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL4073092 | 0.84 | DPP4 (0.62) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL555194 | 0.83 | DPP4 (0.61) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| SCHEMBL557054 | 0.83 | DPP4 (0.52) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL555193 | 0.83 | DPP4 (0.61) | DPP4MAPK1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27582646 | 0.83 | DPP4 (0.61) | DPP4MAPK1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101293888-B | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA | 2013-09-25 | — | — | CN | disclosed |
| CN-101293888-A | Xanthine derivative, production and use thereof as a medicament | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-10-29 | — | — | CN | disclosed |
| CN-100408579-C | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-08-06 | — | — | CN | disclosed |
| CN-1492870-A | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-28 | — | — | CN | disclosed |