Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | ATM | Q13315 | 2/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.66 |
| ▸ | ACP1 | P24666 | 6/20 | 0.66 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17295568 | 0.82 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295569 | 0.82 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL19096570 | 0.79 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295246 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295528 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295526 | 0.77 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295247 | 0.77 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295440 | 0.77 | MAPT (0.62) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295438 | 0.77 | MAPT (0.62) | MEN1KMT2AALDH1A1MAPTATM | |
| SCHEMBL17295330 | 0.75 | MAPT (0.60) | MEN1KMT2AALDH1A1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1657529-A | 2-substituted imine thia zlidine derivative its preparation technology and medicinal composition | SHANGHAI INST PHARM INDUSTRY (CN) | 2005-08-24 | — | — | CN | disclosed |