Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GCLC | P48506 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740180 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GCLCTP53RECQLLMNA | |
| SCHEMBL5739636 | 1.00 | ALDH1A1 (0.43) | ALDH1A1GCLCTP53RECQLLMNA | |
| SCHEMBL5738757 | 0.75 | TSHR (0.41) | TP53 | |
| SCHEMBL2167522 | 0.75 | TSHR (0.41) | TP53 | |
| SCHEMBL5738756 | 0.75 | TP53 (0.36) | GCLCTP53 | |
| SCHEMBL2167519 | 0.75 | TP53 (0.36) | GCLCTP53 | |
| SCHEMBL2380019 | 0.75 | ALDH1A1 (0.68) | ALDH1A1LMNA | |
| SCHEMBL4918402 | 0.73 | — | — | |
| SCHEMBL170745 | 0.73 | — | — | |
| SCHEMBL26305899 | 0.72 | ALDH1A1 (0.48) | ALDH1A1RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482233-C | Compositions and methods for treating amyloidosis | UNIV KINGSTON (CH) | 2009-04-29 | — | — | CN | claimed |
| CN-1523992-A | Compositions and methods for treating amyloidosis | ʺ��ѧ | 2004-08-25 | — | — | CN | claimed |
| CN-101597196-B | Improved drug candidate and preparation method thereof | JIYAKETA CO., LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |
| CN-101597196-A | Improved drug candidate and preparation method thereof | BELLUS HEALTH INTERNAT LTD (CH) | 2009-12-09 | — | — | CN | disclosed |
| CN-100528840-C | Improved drug candidates and methods for their preparation | NEUROCHEM INTERNAT LTD (CH) | 2009-08-19 | — | — | CN | disclosed |
| CN-100482233-C | Compositions and methods for treating amyloidosis | UNIV KINGSTON (CH) | 2009-04-29 | — | — | CN | disclosed |
| CN-1839117-A | Improved drug candidates and methods for their preparation | NEUROCHEM INTERNAT LTD (CH) | 2006-09-27 | — | — | CN | disclosed |
| CN-1523992-A | Compositions and methods for treating amyloidosis | ʺ��ѧ | 2004-08-25 | — | — | CN | disclosed |