Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601267 | 0.86 | EPHX1 (0.49) | KMT2AMEN1NPC1RAB9AADRA2B | |
| SCHEMBL4192667 | 0.86 | EPHX1 (0.49) | KMT2AMEN1NPC1RAB9AADRA2B | |
| SCHEMBL753794 | 0.85 | NR4A2 (0.49) | NR4A2ALDH1A1LMNATDP1 | |
| SCHEMBL13379550 | 0.85 | NR4A2 (0.49) | NR4A2ALDH1A1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL4208521 | 0.85 | EPHX1 (0.47) | KMT2AMEN1NPC1RAB9AADRA2B | |
| Hydrochloric Acid SCHEMBL4198787 | 0.83 | EPHX1 (0.46) | KMT2AMEN1NPC1RAB9AADRA2B | |
| Hydrochloric Acid SCHEMBL4203337 | 0.83 | EPHX1 (0.46) | KMT2AMEN1NPC1RAB9AADRA2B | |
| SCHEMBL4560731 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL2479783 | 0.81 | MEN1 (0.51) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL29018886 | 0.81 | MEN1 (0.51) | KMT2AMEN1NPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1880304-B | Triamide-substituted indoles, benzofuranes and benzothiophenes | PFIZER | 2010-11-24 | — | — | CN | disclosed |
| CN-1522246-B | Triamide-substituted indoles, benzofurans and benzothiophenes | PFIZER | 2010-04-21 | — | — | CN | disclosed |
| CN-1880304-A | Triamide-substituted indoles, benzofuranes and benzothiophenes | PFIZER (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1522246-A | Triamide-substituted indoles, benzofurans and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (APO B) secretion | �Ʒ� | 2004-08-18 | — | — | CN | disclosed |