Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6175614 | 0.87 | MAPT (0.49) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6176759 | 0.87 | RAB9A (0.57) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6172214 | 0.87 | MAPT (0.51) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6174882 | 0.82 | POLB (0.49) | MAPTLMNASMN1; SMN2HTTGAA | |
| SCHEMBL27601314 | 0.80 | KMT2A (0.51) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6174603 | 0.75 | MAPT (0.53) | MAPTLMNASMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL6173338 | 0.74 | RAB9A (0.50) | MAPTLMNASMN1; SMN2KDM4EGAA | |
| SCHEMBL6176630 | 0.72 | RAB9A (0.65) | MAPTLMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL6173268 | 0.72 | RAB9A (0.43) | MAPTSMN1; SMN2KDM4EGAAALDH1A1 | |
| SCHEMBL27601474 | 0.72 | KMT2A (0.41) | MAPTLMNASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1473157-A | Amide derivatives | ֮����ҩ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |