Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.45 |
| ▸ | CTSS | P25774 | 14/20 | 0.44 |
| ▸ | CTSL | P07711 | 13/20 | 0.44 |
| ▸ | CTSB | P07858 | 9/20 | 0.44 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601610 | 0.86 | CTSK (0.43) | CTSKCTSSCTSLCTSB | |
| SCHEMBL2157103 | 0.84 | CTSK (0.65) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL27601607 | 0.81 | CTSK (0.51) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL2157034 | 0.79 | CTSK (0.66) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL4673385 | 0.79 | CTSK (0.47) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL8350199 | 0.77 | CTSK (0.49) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL27601615 | 0.71 | CTSK (0.38) | CTSKCTSSCTSLCTSB | |
| SCHEMBL2156758 | 0.70 | CTSK (0.67) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL2155770 | 0.70 | CTSK (0.84) | CTSKCTSSCTSLCTSBCTSF | |
| SCHEMBL2156272 | 0.70 | CTSK (0.66) | CTSKCTSSCTSLCTSBCTSF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100430052-C | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA INC (CA) | 2008-11-05 | — | — | CN | claimed |
| CN-1638757-A | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA INC (CA) | 2005-07-13 | — | — | CN | claimed |
| CN-100430052-C | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA INC (CA) | 2008-11-05 | — | — | CN | disclosed |
| CN-1638757-A | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA INC (CA) | 2005-07-13 | — | — | CN | disclosed |