SCHEMBL27601700

SCHEMBL27601700

CN(C)c1ccc(Br)c(NN)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.35
KMT2A Q03164 1/20 0.35
MAPK1 P28482 2/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6902104 0.79 GAA (0.30) GAAKMT2A
SCHEMBL6790445 0.75 GAA (0.42) GAAKMT2AMAPK1POLBMAPT
SCHEMBL2443752 0.70 GAA (0.46) GAAKMT2AMAPK1POLBMAPT
SCHEMBL18190317 0.66 GAA (0.43) GAAKMT2AMAPK1POLBMAPT
SCHEMBL11773703 0.65 GAA (0.33) GAAKMT2APOLBMAPT
SCHEMBL21653771 0.64 PTGER4 (0.35)
SCHEMBL28856292 0.64
Bromide SCHEMBL20984240 0.62
Hydrochloric Acid SCHEMBL20985021 0.62
SCHEMBL8927868 0.62 CYP3A4 (0.40) GAAKMT2AMAPK1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1471514-A Novel M-amino-phenylimino-imidazolidone derivatives for treating urinary incontinence ���ָ��Ӣ��ķ�������Ϲ�˾ 2004-01-28 CN disclosed