Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2817198 | 0.83 | ALDH1A1 (0.44) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27601971 | 0.80 | ALDH1A1 (0.42) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| SCHEMBL27584228 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| SCHEMBL2820879 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| Aspartic Acid SCHEMBL28036510 | 0.73 | GRIK1 (0.44) | GRM6 | |
| SCHEMBL1455540 | 0.70 | ALDH1A1 (0.65) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| SCHEMBL1985248 | 0.69 | ALDH1A1 (0.46) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 | |
| SCHEMBL27373788 | 0.69 | KMT2A (0.47) | ALDH1A1GABBR2GABBR1SMN1; SMN2NPC1 | |
| SCHEMBL27837573 | 0.69 | DAO (0.44) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1984518 | 0.69 | ALDH1A1 (0.45) | ALDH1A1HPGDNPSR1CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540538-C | High Conductivity Calcium-Activated K Channel Opener | TANABE SEIYAKU CO (JP) | 2009-09-16 | — | — | CN | disclosed |
| CN-1503786-A | High Conductivity Calcium-Activated K Channel Opener | ������ҩ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |