Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 16/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585106 | 0.94 | CXCR2 (0.41) | CXCR2CYP2C9MEN1KMT2AL3MBTL1 | |
| SCHEMBL27585100 | 0.90 | CXCR2 (0.39) | CXCR2CYP2C9 | |
| SCHEMBL27602918 | 0.89 | CXCR2 (0.41) | CXCR2CYP2C9L3MBTL1 | |
| SCHEMBL27602916 | 0.88 | CXCR2 (0.39) | CXCR2CYP2C9MEN1KMT2AL3MBTL1 | |
| SCHEMBL27585104 | 0.87 | CXCR2 (0.41) | CXCR2CYP2C9L3MBTL1 | |
| SCHEMBL27585094 | 0.87 | CXCR2 (0.41) | CXCR2CYP2C9MEN1KMT2A | |
| SCHEMBL27585248 | 0.86 | CXCR2 (0.36) | CXCR2CYP2C9MEN1KMT2AL3MBTL1 | |
| SCHEMBL27602912 | 0.85 | CXCR2 (0.37) | CXCR2CYP2C9L3MBTL1 | |
| SCHEMBL27585097 | 0.84 | L3MBTL1 (0.41) | CXCR2MEN1KMT2AL3MBTL1RORC | |
| SCHEMBL27585099 | 0.83 | L3MBTL1 (0.35) | CXCR2MEN1KMT2AL3MBTL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1496348-A | 5-cyano-1H-indole derivatives as antagonists of interleukine-8 receptors | ʵ���Ҹ���Ү��˾ | 2004-05-12 | — | — | CN | disclosed |