Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 17/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 17/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 17/20 | 0.61 |
| ▸ | PRKDC | P78527 | 17/20 | 0.61 |
| ▸ | ABL1 | P00519 | 16/20 | 0.61 |
| ▸ | EGFR | P00533 | 16/20 | 0.61 |
| ▸ | HCK | P08631 | 16/20 | 0.61 |
| ▸ | KDR | P35968 | 16/20 | 0.61 |
| ▸ | MTOR | P42345 | 16/20 | 0.61 |
| ▸ | EPHB4 | P54760 | 15/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.61 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804210 | 0.85 | SRC (0.69) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24096567 | 0.81 | SRC (0.61) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL6434464 | 0.79 | LCK (0.56) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL6431342 | 0.79 | LCK (0.56) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24196618 | 0.78 | BTK (0.63) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30416266 | 0.78 | BTK (0.63) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL27586575 | 0.77 | LCK (0.53) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24096758 | 0.77 | PIK3CD (0.69) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL29998830 | 0.77 | PIK3CD (0.69) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL23997162 | 0.77 | EGFR (0.61) | SRCPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |