Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156537 | 0.80 | MGLL (0.52) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL13623152 | 0.77 | CYP3A4 (0.50) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL13801959 | 0.77 | CYP3A4 (0.50) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL30844047 | 0.77 | CYP3A4 (0.50) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL27498370 | 0.77 | CYP3A4 (0.50) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL31370757 | 0.76 | AURKA (0.50) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL6965973 | 0.76 | CYP3A4 (0.49) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL13735759 | 0.76 | CYP3A4 (0.49) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL16246164 | 0.76 | CYP3A4 (0.49) | AURKARPS6KB1CYP3A4CYP2C19MGLL | |
| SCHEMBL1025361 | 0.76 | CYP3A4 (0.46) | AURKARPS6KB1CYP3A4CYP2C19MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535155-A | A combination comprising -2-ethoxy-3- [ 4- (2- { 4-methanesulfonyloxyphenyl } ethoxy) phenyl ] propanoic acid or 3- { 4- [ 2- (4-tert-butoxycarbonylaminophenyl) ethoxy ] phenyl } - -2-ethoxypropanoic acid and insulin | — | 2004-10-06 | — | — | CN | disclosed |