Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 18/20 | 0.50 |
| ▸ | CDK1 | P06493 | 18/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 18/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 18/20 | 0.50 |
| ▸ | GSK3B | P49841 | 16/20 | 0.50 |
| ▸ | GSK3A | P49840 | 13/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 11/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 11/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | INSR | P06213 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779800 | 0.83 | CCNB2 (0.52) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL27613634 | 0.81 | CCNB2 (0.50) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL2760594 | 0.79 | CCNB2 (0.48) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1777955 | 0.78 | CCNB2 (0.54) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL27843742 | 0.68 | PPARG (0.47) | — | |
| SCHEMBL27615789 | 0.68 | CCNB2 (0.60) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL1777165 | 0.65 | CCNB2 (0.56) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL491112 | 0.63 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL29912855 | 0.63 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B | |
| SCHEMBL490933 | 0.63 | CCNB2 (1.00) | CCNB2CDK1CCNB1CCNB3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2233486-A1 | Azaindoles | Aventis Pharma Limited (GB) | 2010-09-29 | — | — | EP | disclosed |