Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15563577 | 0.83 | TAAR1 (0.45) | DAOPNMTTAAR1PIK3CARPA1 | |
| SCHEMBL5650950 | 0.83 | PIK3CA (0.47) | DAOPNMTTAAR1PIK3CARPA1 | |
| SCHEMBL793707 | 0.81 | TAAR1 (0.69) | DAOPNMTTAAR1SIGMAR1GAA | |
| SCHEMBL23850015 | 0.81 | TAAR1 (0.47) | DAOPNMTTAAR1PIK3CARPA1 | |
| SCHEMBL7328450 | 0.80 | PNMT (0.61) | DAOPNMTTAAR1SIGMAR1MEN1 | |
| SCHEMBL530440 | 0.79 | DAO (0.45) | DAOPNMTTAAR1PIK3CATSHR | |
| Hydrochloric Acid SCHEMBL3271461 | 0.79 | TAAR1 (0.67) | DAOPNMTTAAR1SIGMAR1GAA | |
| SCHEMBL3264645 | 0.79 | MAPT (0.47) | DAOPNMTTAAR1PIK3CARPA1 | |
| SCHEMBL17552730 | 0.79 | TAAR1 (0.45) | DAOPNMTTAAR1PIK3CARPA1 | |
| SCHEMBL27814750 | 0.79 | TAAR1 (0.45) | DAOPNMTTAAR1PIK3CARPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668601-A | N-substituted tricyclic 3-aminopyrazoles as PDFG receptor inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2005-09-14 | — | — | CN | disclosed |