Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495413 | 0.92 | NR1I2 (0.47) | NR1I2CYP2C9ADORA2ASCN9ASCN5A | |
| SCHEMBL2760611 | 0.89 | NR1I2 (0.43) | NR1I2CYP2C9P2RX7SCN9ASCN5A | |
| SCHEMBL2760665 | 0.89 | P2RX3 (0.44) | ALDH1A1P2RX7P2RX3P2RX2 | |
| SCHEMBL2760575 | 0.87 | P2RX3 (0.47) | ALDH1A1P2RX7P2RX3P2RX2LMNA | |
| SCHEMBL2760748 | 0.83 | NR1I2 (0.49) | NR1I2CYP2C9ALDH1A1P2RX7P2RX3 | |
| SCHEMBL12757539 | 0.82 | SCN5A (0.49) | ALDH1A1ADORA2ASCN9ASCN5A | |
| SCHEMBL1495384 | 0.81 | NR1I2 (0.44) | NR1I2CYP2C9SCN9ASCN5AP2RX3 | |
| SCHEMBL1495389 | 0.81 | NR1I2 (0.44) | NR1I2CYP2C9SCN9ASCN5AP2RX3 | |
| SCHEMBL1495751 | 0.81 | NR1I2 (0.71) | NR1I2CYP2C9P2RX3P2RX2 | |
| SCHEMBL12757587 | 0.80 | HCRTR1 (0.47) | P2RX7P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | claimed |