Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170510 | 0.85 | P2RX3 (0.52) | P2RX3P2RX2P2RX7TRPV1KMT2A | |
| SCHEMBL2760599 | 0.85 | P2RX3 (0.47) | P2RX3P2RX2P2RX7MAPTTRPV1 | |
| SCHEMBL2760681 | 0.84 | P2RX3 (0.46) | P2RX3P2RX2P2RX7TRPV1NPC1 | |
| SCHEMBL2760581 | 0.83 | P2RX3 (0.43) | P2RX3P2RX2P2RX7MAPTTRPV1 | |
| SCHEMBL2760582 | 0.83 | P2RX3 (0.43) | P2RX3P2RX2P2RX7MAPTTRPV1 | |
| SCHEMBL2760575 | 0.81 | P2RX3 (0.47) | P2RX3P2RX2P2RX7TP53ALDH1A1 | |
| SCHEMBL2760722 | 0.80 | P2RX3 (0.49) | P2RX3P2RX2P2RX7MAPTPOLB | |
| SCHEMBL2760721 | 0.80 | P2RX3 (0.49) | P2RX3P2RX2P2RX7MAPTPOLB | |
| SCHEMBL2171270 | 0.79 | P2RX3 (0.71) | P2RX3P2RX2 | |
| SCHEMBL2171429 | 0.79 | P2RX3 (0.46) | P2RX3P2RX2P2RX7TRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |