SCHEMBL27607016

SCHEMBL27607016

O=CCc1ccc2cc[nH]c2c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.56
AHR P35869 3/20 0.47
CMA1 P23946 1/20 0.47
TYR P14679 1/20 0.47
ENPP2 Q13822 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
BACE1 P56817 5/20 0.46
NLRP3 Q96P20 3/20 0.43
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
FAAH O00519 1/20 0.40
GPR84 Q9NQS5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28755927 0.85 CYP2A6 (0.56) CYP2A6AHR
SCHEMBL28311634 0.80 AHR (0.50) CYP2A6AHRCMA1TYRENPP2
SCHEMBL11574440 0.79 TYR (0.46) CYP2A6AHRCMA1TYRENPP2
SCHEMBL27613423 0.79 CYP2A6 (0.50) CYP2A6AHRCMA1TYRENPP2
Formic Acid SCHEMBL31513818 0.79 CYP2A6 (0.50) CYP2A6AHRCMA1TYRENPP2
SCHEMBL27891513 0.79 ENPP2 (0.49) CYP2A6AHRCMA1TYRENPP2
SCHEMBL27657201 0.79 ENPP2 (0.49) CYP2A6AHRCMA1TYRENPP2
SCHEMBL31271 0.76 AHR (0.50) CYP2A6AHRCMA1TYRENPP2
SCHEMBL13978582 0.76 AHR (0.55) CYP2A6AHRCMA1TYRENPP2
SCHEMBL5390737 0.76 AHR (0.55) CYP2A6AHRCMA1TYRENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1657551-A Copolymer compound and electrochemical cell therewith NEC TOKIN CO LTD (JP) 2005-08-24 CN disclosed