Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL30530223 | 0.90 | TSHR (0.30) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL29359954 | 0.90 | TSHR (0.30) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL18210482 | 0.82 | TSHR (0.36) | TSHRNAPRTTDP1CYP11B2 | |
| SCHEMBL21351710 | 0.81 | — | — | |
| Pyridine SCHEMBL28304390 | 0.81 | TSHR (0.35) | TSHRNAPRTTDP1CYP11B2 | |
| Pyridine SCHEMBL4381079 | 0.81 | TSHR (0.35) | TSHRNAPRTTDP1CYP11B2 | |
| SCHEMBL28417174 | 0.76 | — | — | |
| Benzene SCHEMBL9464137 | 0.76 | KDM4E (0.30) | — | |
| Pyridine SCHEMBL6100271 | 0.73 | SMN1; SMN2 (0.33) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL2121675 | 0.68 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100528850-C | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | BAYER AG (US) | 2009-08-19 | — | — | CN | claimed |
| CN-1558905-A | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | ������˹ҩƷ��˾ | 2004-12-29 | — | — | CN | claimed |
| CN-100591657-C | Indane acetic acid compound | BAYER PHARMACEUTICALS CORP | 2010-02-24 | — | — | CN | disclosed |
| CN-100528850-C | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | BAYER AG (US) | 2009-08-19 | — | — | CN | disclosed |
| CN-1854118-A | Indane acetic acid compound | BAYER PHARMACEUTICALS CORP (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1558905-A | Indane acetic acid derivatives, their use as medicaments, intermediates and processes for their preparation | ������˹ҩƷ��˾ | 2004-12-29 | — | — | CN | disclosed |