SCHEMBL27608255

SCHEMBL27608255

CCO[Si](OCC)(OCC)C(=O)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.50
MAOB P27338 2/20 0.50
MAOA P21397 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GLA P06280 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 4/20 0.48
LMNA P02545 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HDAC3 O15379 2/20 0.48
HDAC4 P56524 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
PLIN1 O60240 2/20 0.48
RECQL P46063 2/20 0.48
PLIN5 Q00G26 2/20 0.48
ABHD5 Q8WTS1 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27608254 1.00 NPC1 (0.50) NPC1MAOBMAOAL3MBTL1GLA
SCHEMBL27627437 0.81 GLA (0.55) NPC1MAOBMAOAL3MBTL1GLA
SCHEMBL27627438 0.81 GLA (0.55) NPC1MAOBMAOAL3MBTL1GLA
SCHEMBL296535 0.78 LMNA (0.50) NPC1MAOBMAOAL3MBTL1GLA
SCHEMBL296536 0.78 LMNA (0.50) NPC1MAOBMAOAL3MBTL1GLA
Ethyl Cinnamate SCHEMBL12001792 0.74 CA12 (0.72) NPC1MAOBL3MBTL1GLATDP1
Ethyl Cinnamate SCHEMBL1866942 0.74 CA12 (0.72) NPC1MAOBL3MBTL1GLATDP1
Ethyl Cinnamate SCHEMBL112446 0.74 CA12 (0.72) NPC1MAOBL3MBTL1GLATDP1
Ethyl Cinnamate SCHEMBL112445 0.74 CA12 (0.72) NPC1MAOBL3MBTL1GLATDP1
Cinnamic Acid SCHEMBL30320241 0.74 HCAR2 (0.70) NPC1MAOBMAOAL3MBTL1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100501532-C Liquid crystal directing agent, liquid crystal oriented film and liquid crystal display element JSR CORP (JP) 2009-06-17 CN disclosed
CN-1664657-A Liquid crystal directing agent, liquid crystal oriented film and liquid crystal indicator element JSR CORP (JP) 2005-09-07 CN disclosed