SCHEMBL2760838

SCHEMBL2760838

Oc1c(-c2cccs2)sc(-c2cccs2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
DPP4 P27487 2/20 0.42
RPS6KB2 Q9UBS0 1/20 0.42
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 5/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 3/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 4/20 0.41
GLA P06280 2/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 3/20 0.41
CASP1 P29466 3/20 0.41
CASP7 P55210 3/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
USP2 O75604 2/20 0.41
TSHR P16473 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4319170 0.78 MEN1 (0.47) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL7132180 0.76 MEN1 (0.46) MEN1KMT2ADPP4RPS6KB2ALDH1A1
SCHEMBL14832753 0.76 MEN1 (0.46) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL650323 0.76 MEN1 (0.46) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL1086309 0.76 MEN1 (0.55) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL28832894 0.76 RPS6KB2 (0.43) MEN1KMT2ARPS6KB2ALDH1A1KDM4E
SCHEMBL18133656 0.73 ERN1 (0.50) MEN1KMT2ADPP4RPS6KB2ALDH1A1
SCHEMBL12892637 0.73 MEN1 (0.43) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL2495541 0.73 FBP1 (0.45) MEN1KMT2ADPP4ALDH1A1KDM4E
SCHEMBL20656172 0.73 DPP4 (0.49) MEN1KMT2ADPP4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100324306-A1 ELECTROCHROMIC MATERIALS UNIVERSITY OF WASHINGTON (US) 2010-12-23 US claimed
US-20090067030-A1 SYNTHESIS OF GREEN ELECTROCHROMIC MATERIALS UNIVERSITY OF WASHINGTON (US) 2009-03-12 US claimed
EP-3036305-B1 COMPOUNDS WITH TERMINAL HETEROARYLCYANOVINYLENE GROUPS AND THEIR USE IN ORGANIC SOLAR CELLS BASF SE (DE) 2019-04-17 EP disclosed