Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220500 | 0.80 | MAPK14 (0.50) | MAPK14MAPK11MAPK13MAPK12CSNK1D | |
| SCHEMBL27627887 | 0.79 | MAPK14 (0.44) | MAPK14MAPK11MAPK13MAPK12HTR3A | |
| SCHEMBL27608556 | 0.79 | MAPK14 (0.52) | MAPK14MAPK11MAPK13MAPK12HTR3A | |
| SCHEMBL27627894 | 0.79 | MAPK14 (0.44) | MAPK14MAPK11MAPK13MAPK12HTR3A | |
| SCHEMBL6219664 | 0.77 | MAPK14 (0.49) | MAPK14MAPK11MAPK13MAPK12CSNK1D | |
| SCHEMBL6375585 | 0.77 | HTR3A (0.55) | MAPK14MAPK11MAPK13MAPK12CSNK1D | |
| SCHEMBL25222456 | 0.76 | IKBKB (0.49) | MAPK14MAPK11MAPK13MAPK12CSNK1D | |
| SCHEMBL27627754 | 0.75 | MAPK14 (0.45) | MAPK14MAPK11MAPK13MAPK12IKBKB | |
| SCHEMBL27627755 | 0.75 | MAPK14 (0.45) | MAPK14MAPK11MAPK13MAPK12IKBKB | |
| SCHEMBL25611852 | 0.75 | MAPK14 (0.55) | MAPK14MAPK11MAPK13MAPK12CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1701069-A | 3,4-disubstituted pyrroles and their for use in treating inflammatory diseases | JANSSEN PHARMACEUTICA NV (BE) | 2005-11-23 | — | — | CN | disclosed |