SCHEMBL27608932

SCHEMBL27608932

Nc1ncccc1-c1ncccc1-c1cccnc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.50
PTGS2 P35354 1/20 0.49
MAP4K4 O95819 1/20 0.49
TDO2 P48775 1/20 0.47
CYP3A4 P08684 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
CHEK2 O96017 1/20 0.46
MKNK1 Q9BUB5 2/20 0.45
MKNK2 Q9HBH9 2/20 0.45
NUDT1 P36639 1/20 0.44
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
PTK2 Q05397 1/20 0.44
MEN1 O00255 1/20 0.43
PSIP1 O75475 1/20 0.43
AXL P30530 1/20 0.43
CDK5 Q00535 1/20 0.43
CDK5R1 Q15078 1/20 0.43
BACE1 P56817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3949315 0.89 MAP4K4 (0.59) CYP2A6MAP4K4TDO2CYP3A4ALDH1A1
SCHEMBL29576461 0.89 MAP4K4 (0.59) CYP2A6MAP4K4TDO2CYP3A4ALDH1A1
SCHEMBL11067761 0.84 PTGS2 (0.60) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
Hydrazine SCHEMBL27511993 0.84 PTGS2 (0.60) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
SCHEMBL28181896 0.83 PTGS2 (0.64) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
SCHEMBL30032 0.83 PTGS2 (0.64) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
SCHEMBL31635952 0.83 PTGS2 (0.64) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
Methylamine SCHEMBL28462146 0.82 PTGS2 (0.63) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
Hydrochloric Acid SCHEMBL17533979 0.82 PTGS2 (0.62) CYP2A6PTGS2TDO2CYP3A4ALDH1A1
SCHEMBL1323698 0.82 PTGS2 (0.62) CYP2A6PTGS2TDO2CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1795202-B Metal chelate complexes immobilized on solid supports for peptide preparation APLAGEN GMBH 2010-05-26 CN claimed
CN-101450925-A Photosensitive 4'-(4-diazo) phenyl (2,2':6',2'')-terpyridyl fluoroborate, preparation method thereof and decoration to sheet substrate surface BEIJING INST TECHNOLOGY (CN) 2009-06-10 CN claimed
CN-1795202-A Metal chelate complexes immobilized on solid supports for peptide preparation APLAGEN GMBH (DE) 2006-06-28 CN claimed
CN-105300940-A Fluorescent probe for zinc ion and cadmium ion detection as well as preparation method and application of fluorescent probe UNIV DALIAN TECH 2016-02-03 CN disclosed
CN-1795202-B Metal chelate complexes immobilized on solid supports for peptide preparation APLAGEN GMBH 2010-05-26 CN disclosed
CN-100567471-C Use of metal complexes as oxidation catalysts CIBA SC HOLDING AG (CH) 2009-12-09 CN disclosed
CN-101450925-A Photosensitive 4'-(4-diazo) phenyl (2,2':6',2'')-terpyridyl fluoroborate, preparation method thereof and decoration to sheet substrate surface BEIJING INST TECHNOLOGY (CN) 2009-06-10 CN disclosed
CN-1795202-A Metal chelate complexes immobilized on solid supports for peptide preparation APLAGEN GMBH (DE) 2006-06-28 CN disclosed
CN-1646672-A Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG (CH) 2005-07-27 CN disclosed