Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767231 | 0.71 | MEN1 (0.43) | GSK3BHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1025579 | 0.71 | BCHE (0.35) | GSK3B | |
| SCHEMBL6867284 | 0.66 | PIM1 (0.69) | PIM1 | |
| SCHEMBL29142651 | 0.66 | CES1 (0.42) | GSK3BPPARG | |
| SCHEMBL21803246 | 0.65 | KDM1A (0.39) | GSK3B | |
| SCHEMBL29221349 | 0.64 | MAOA (0.34) | PIM1GSK3B | |
| SCHEMBL29221320 | 0.64 | GSK3B (0.45) | GSK3BPPARG | |
| SCHEMBL6233173 | 0.64 | GSK3B (0.41) | GSK3B | |
| SCHEMBL10602240 | 0.64 | GSK3B (0.41) | GSK3B | |
| SCHEMBL11547662 | 0.63 | GSK3B (0.40) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |