Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.55 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.49 |
| ▸ | HNF4A | P41235 | 2/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569383 | 0.87 | ACMSD (0.68) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1250065 | 0.85 | ACMSD (0.57) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1250945 | 0.84 | ACMSD (0.68) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1250277 | 0.84 | MCL1 (0.68) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1510280 | 0.83 | ACMSD (0.70) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1249257 | 0.81 | SMN1; SMN2 (0.53) | ACMSDLCKMCL1MEN1KMT2A | |
| SCHEMBL1249395 | 0.81 | ACMSD (0.53) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL1247843 | 0.81 | ACMSD (0.53) | ACMSDLCKMCL1HNF4ADHFR | |
| SCHEMBL9067649 | 0.78 | GRIN2D (0.46) | ACMSDGRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL6692918 | 0.77 | MEN1 (0.50) | ACMSDLCKMCL1HNF4ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1558762-A | Novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer | ŵ��Ų�ڿ˹�˾ | 2004-12-29 | — | — | CN | disclosed |