Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5966250 | 0.98 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2CYP1A2GPBAR1NCF1 | |
| SCHEMBL103909 | 0.79 | PDE10A (0.46) | CYSLTR1CYSLTR2CYP1A2PDE10A | |
| SCHEMBL1078145 | 0.78 | MEN1 (0.59) | CYSLTR1CYSLTR2CYP1A2GPBAR1NCF1 | |
| SCHEMBL349015 | 0.78 | CYP1A2 (0.49) | CYSLTR1CYSLTR2CYP1A2GPBAR1NCF1 | |
| SCHEMBL1779691 | 0.78 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2CYP1A2GPBAR1NCF1 | |
| SCHEMBL243295 | 0.75 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2CYP1A2GPBAR1NCF1 | |
| SCHEMBL2913941 | 0.74 | PDE10A (0.61) | CYSLTR1CYSLTR2CYP1A2NCF1NOS2 | |
| SCHEMBL3267444 | 0.74 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2CYP1A2NCF1NOS2 | |
| SCHEMBL30879956 | 0.74 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2CYP1A2NCF1NOS2 | |
| Anthracene SCHEMBL10455883 | 0.74 | MAPT (0.54) | CYSLTR1CYSLTR2CYP1A2GPBAR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100393836-C | Conductive adhesive composition with electrical stability and good impact resistance for electronic devices | NAT STARCH CHEM INVEST (US) | 2008-06-11 | — | — | CN | claimed |
| CN-1788062-A | Conductive adhesive compositions with electrical stability and good impact resistance for use in electronics devices | NAT STARCH CHEM INVEST (US) | 2006-06-14 | — | — | CN | claimed |
| CN-100511490-C | Electrically conductive materials with electrical stability for use in electronic devices | NAT STARCH CHEM INVEST (US) | 2009-07-08 | — | — | CN | disclosed |
| CN-100393836-C | Conductive adhesive composition with electrical stability and good impact resistance for electronic devices | NAT STARCH CHEM INVEST (US) | 2008-06-11 | — | — | CN | disclosed |
| CN-1788062-A | Conductive adhesive compositions with electrical stability and good impact resistance for use in electronics devices | NAT STARCH CHEM INVEST (US) | 2006-06-14 | — | — | CN | disclosed |
| CN-1693404-A | Compositions for use in electronics devices | NAT STARCH CHEM INVEST (US) | 2005-11-09 | — | — | CN | disclosed |