SCHEMBL1078145

SCHEMBL1078145

N#CCc1ccc2ccccc2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
CYSLTR1 Q9Y271 3/20 0.49
CYSLTR2 Q9NS75 1/20 0.49
CYP1A2 P05177 2/20 0.45
PDE10A Q9Y233 3/20 0.42
NCF1 P14598 1/20 0.42
NOS2 P35228 1/20 0.42
BACE1 P56817 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
GPBAR1 Q8TDU6 2/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthracene SCHEMBL10455883 0.94 MAPT (0.54) MEN1MAPTKMT2ACYSLTR1CYSLTR2
SCHEMBL31225180 0.81 PDE10A (0.46) MEN1MAPTKMT2ACYSLTR1CYSLTR2
SCHEMBL349015 0.80 CYP1A2 (0.49) CYSLTR1CYSLTR2CYP1A2PDE10ANCF1
SCHEMBL5966250 0.80 CYSLTR1 (0.49) CYSLTR1CYSLTR2CYP1A2PDE10ANCF1
SCHEMBL1779691 0.80 CYSLTR1 (0.49) CYSLTR1CYSLTR2CYP1A2PDE10ANCF1
Bromide SCHEMBL27610232 0.78 CYSLTR1 (0.47) CYSLTR1CYSLTR2CYP1A2PDE10ANCF1
SCHEMBL9301876 0.77 CYSLTR1 (0.68) CYSLTR1CYSLTR2PDE10AGPBAR1
SCHEMBL2913941 0.76 PDE10A (0.61) CYSLTR1CYSLTR2CYP1A2PDE10ANCF1
SCHEMBL3267444 0.76 CYSLTR1 (0.57) MAPTCYSLTR1CYSLTR2CYP1A2PDE10A
SCHEMBL30879956 0.76 CYSLTR1 (0.57) MAPTCYSLTR1CYSLTR2CYP1A2PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174991-A Fluorescent dye excited and emitted by second window in near infrared region, and preparation method and application thereof 复旦大学 2021-01-05 CN claimed
US-9469741-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2016-10-18 US claimed
EP-2203482-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORP (JP) 2015-11-25 EP claimed
CN-104945540-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2015-09-30 CN claimed
US-20150267031-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2015-09-24 US claimed
US-9085646-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2015-07-21 US claimed
US-20130066016-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-14 US claimed
US-8362156-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2013-01-29 US claimed
US-8314189-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2012-11-20 US claimed
US-20100280217-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-11-04 US claimed
CN-101874044-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2010-10-27 CN claimed
EP-2203482-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2010-07-07 EP claimed
WO-2009051702-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-04-23 WO claimed
WO-2009051700-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (US) 2009-04-23 WO claimed
US-20090099325-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION 2009-04-16 US claimed
WO-2026102105-A1 FUNCTIONAL POLYBUTADIENE AND CARBON BLACK IN RUBBER COMPOUNDS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2026-05-15 WO disclosed
CN-119823118-A Near infrared fluorescent photosensitizer based on benzoselenadiazole and acrylonitrile, preparation method and application 淮阴工学院 2025-04-15 CN disclosed
EP-0041623-A2 Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1981-12-16 EP disclosed
EP-0041624-A2 Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof AMERICAN CYANAMID COMPANY (US) 1981-12-16 EP disclosed
US-4268668-A FOR WOOL AND POLYAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed