Flavanone

Flavanone

SCHEMBL27610364

COC.O=C1CC(c2ccccc2)Oc2ccccc21

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.87
AR P10275 3/20 0.87
CYP19A1 P11511 3/20 0.87
ADORA3 P0DMS8 2/20 0.87
KDM4E B2RXH2 2/20 0.87
HSD17B10 Q99714 2/20 0.87
NPC1 O15118 2/20 0.78
MAPT P10636 2/20 0.78
RAB9A P51151 2/20 0.78
CYP3A4 P08684 1/20 0.70
MAPK1 P28482 1/20 0.70
ABCB1 P08183 1/20 0.68
ABCG2 Q9UNQ0 1/20 0.68
ALDH1A1 P00352 1/20 0.63
HPGD P15428 1/20 0.63
MAOA P21397 1/20 0.60
PSMB5 P28074 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavanone SCHEMBL29470801 0.93 MAOB (1.00) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL19745 0.93 MAOB (1.00) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL12660199 0.93 MAOB (1.00) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL29843289 0.93 MAOB (1.00) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL12189591 0.93 MAOB (1.00) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL27610362 0.92 MAOB (0.90) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL11733114 0.92 MAOB (0.96) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL27281921 0.92 MAOB (0.96) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL22715765 0.92 MAOB (0.96) MAOBARCYP19A1ADORA3KDM4E
Flavanone SCHEMBL27291349 0.92 MAOB (0.96) MAOBARCYP19A1ADORA3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111892567-B Dihydroflavonoid compound extracted from lindera reflexa hemsl, and preparation method and application thereof 河南中医药大学 2024-01-26 CN claimed
CN-117384125-A Ciliate resistant active ingredient in fructus psoraleae and application thereof 大连海洋大学 2024-01-12 CN claimed
CN-116270605-A Application of psoralen dihydroflavone methyl ether in preparing medicament for treating leucopenia 中国人民解放军海军军医大学 2023-06-23 CN claimed
CN-112816594-A Method for measuring contents of 18 chemical components in fructus psoraleae medicinal material 天津中医药大学 2021-05-18 CN claimed
CN-111892567-A Flavanone compound extracted from lindera reflexa hemsl and preparation method and application thereof 河南中医药大学 2020-11-06 CN claimed
CN-118217325-A Danzhiqing tablet dry extract and preparation method thereof 华润三九医药股份有限公司 2024-06-21 CN disclosed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
CN-111892567-B Dihydroflavonoid compound extracted from lindera reflexa hemsl, and preparation method and application thereof 河南中医药大学 2024-01-26 CN disclosed
CN-111892567-B Dihydroflavonoid compound extracted from lindera reflexa hemsl, and preparation method and application thereof 河南中医药大学 2024-01-26 CN disclosed
CN-117384125-A Ciliate resistant active ingredient in fructus psoraleae and application thereof 大连海洋大学 2024-01-12 CN disclosed
CN-116990469-A Verification method for screening heterogeneous liver injury components of epimedium herb and bakuchiol 中国医学科学院肿瘤医院 2023-11-03 CN disclosed
CN-116270605-A Application of psoralen dihydroflavone methyl ether in preparing medicament for treating leucopenia 中国人民解放军海军军医大学 2023-06-23 CN disclosed
CN-103724309-A Fructus psoraleae dihydroflavone methyl ether hydroxylation derivative and synthesis method thereof UNIV TIANJIN SCIENCE & TECH 2014-04-16 CN disclosed
CN-103146804-A Specificity probe zymolyte of glucuronic acid transferase UGT1A1 and application DALIAN CHEMICAL PHYSICS INST 2013-06-12 CN disclosed
CN-103083603-A pharmaceutical composition with functions of intelligence benefiting and kidney warming and preparation method thereof LIN NAN 2013-05-08 CN disclosed
CN-102380013-A Medicinal composition for treating threatened abortion and habitual abortion and preparation method thereof DALIAN PHARMACEUTICAL CO LTD OF JILIN AODONG MEDICINE INDUSTRY GROUP CO LTD 2012-03-21 CN disclosed
CN-102370714-A Medicine composition capable of tonifying brain and soothing nerves and preparation method thereof DALIAN PHARMACEUTICAL CO LTD OF JILIN AODONG MEDICINE INDUSTRY GROUP CO LTD 2012-03-14 CN disclosed
CN-101249088-A Uses of psoralea flavanone methyl ether for preparing antineoplastic, osteoporosis and senile dementia medicament BEIJING KUNAOJI MEDICAL TECHNO (CN) 2008-08-27 CN disclosed
CN-100358543-C Combination of medication for treating osteoporosis and preparation method RONGPING YANG (CN) 2008-01-02 CN disclosed
CN-1695714-A Combination of medication for treating osteoporosis and preparation method YANG RONGPING (CN) 2005-11-16 CN disclosed