Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.59 |
| ▸ | PTPRF | P10586 | 1/20 | 0.59 |
| ▸ | IKBKB | O14920 | 3/20 | 0.56 |
| ▸ | PTPRA | P18433 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12357351 | 0.99 | PTPN1 (0.61) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL614118 | 0.89 | CDC7 (0.54) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL2157963 | 0.86 | IKBKB (0.54) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL12922055 | 0.86 | IKBKB (0.54) | PTPN1PTPRFIKBKBMEN1MAPT | |
| SCHEMBL13270878 | 0.81 | PTPN1 (0.46) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL614262 | 0.79 | CDC7 (0.65) | IKBKB | |
| SCHEMBL2158083 | 0.79 | PTPN1 (0.58) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL23451959 | 0.78 | KDM4E (0.57) | PTPN1IKBKBPOLBMAPT | |
| SCHEMBL2158574 | 0.78 | PTPN1 (0.51) | PTPN1PTPRFIKBKBPTPRAMEN1 | |
| SCHEMBL612007 | 0.77 | MAPT (0.56) | IKBKBPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624391-A | Thiophene derivatives as antiviral agents for flavivirus infection | VIROCHEM PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| CN-100509797-C | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2009-07-08 | — | — | CN | disclosed |
| CN-1602308-A | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2005-03-30 | — | — | CN | disclosed |