Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314750 | 0.78 | EGFR (0.47) | ALDH1A1HPGDSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL196765 | 0.74 | CYP3A4 (0.73) | ALDH1A1KDM4ECYP3A4DYRK1ACLK4 | |
| SCHEMBL29489425 | 0.74 | CYP3A4 (0.73) | ALDH1A1KDM4ECYP3A4DYRK1ACLK4 | |
| SCHEMBL511213 | 0.74 | PDE4A (0.59) | ALDH1A1HPGDSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL5460064 | 0.73 | CA12 (0.48) | ALDH1A1CYP4F2CYP4A11NPC1RAB9A | |
| SCHEMBL2045217 | 0.73 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL5474340 | 0.73 | NR4A1 (0.44) | CYP1A1CYP1A2CYP1B1NOTUMSLC9A1 | |
| SCHEMBL29628977 | 0.72 | CYP3A4 (0.77) | ALDH1A1CYP3A4DYRK1ACLK4CYP1A1 | |
| Hydrogen Sulfide SCHEMBL28640169 | 0.72 | CYP3A4 (0.70) | ALDH1A1KDM4ECYP3A4DYRK1ACLK4 | |
| Ammonia Solution, Strong SCHEMBL27960505 | 0.72 | CYP3A4 (0.70) | ALDH1A1KDM4ECYP3A4DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |