Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.59 |
| ▸ | HTR2C | P28335 | 10/20 | 0.55 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20840816 | 0.93 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL2461209 | 0.89 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL5450499 | 0.86 | PNMT (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL18336575 | 0.84 | PNMT (0.41) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL27983855 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL12954599 | 0.82 | PNMT (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL3750890 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL19139907 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL10864121 | 0.81 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A | |
| SCHEMBL12835831 | 0.81 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101878217-B | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO LTD | 2014-01-15 | — | — | CN | disclosed |
| CN-101878217-A | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO LTD | 2010-11-03 | — | — | CN | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |