Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593313 | 0.84 | HIF1A (0.41) | CHRM2ACHESLC2A1TP53 | |
| SCHEMBL6035455 | 0.83 | CRBN (0.47) | CHRM2BCHEACHETP53 | |
| SCHEMBL13987377 | 0.82 | ACHE (0.58) | CHRM2BCHEACHESLC2A1MTNR1A | |
| SCHEMBL6035179 | 0.82 | HDAC3 (0.48) | CHRM2BCHEACHEGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL4860049 | 0.82 | CRBN (0.47) | CHRM2BCHEACHETP53 | |
| Hydrochloric Acid SCHEMBL4850161 | 0.82 | ACHE (0.57) | CHRM2BCHEACHESLC2A1MTNR1A | |
| Hydrochloric Acid SCHEMBL4852342 | 0.81 | HDAC3 (0.48) | CHRM2BCHEACHETP53CHRM4 | |
| SCHEMBL6034791 | 0.81 | POLB (0.45) | CHRM2BCHEACHESLC2A1MTNR1A | |
| SCHEMBL6035845 | 0.80 | ACHE (0.42) | CHRM2BCHEACHESLC2A1MTNR1A | |
| Hydrochloric Acid SCHEMBL4860176 | 0.80 | POLB (0.44) | CHRM2BCHEACHESLC2A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1589153-A | Prevention or treatment of urinary disorders | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-03-02 | — | — | CN | disclosed |