Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28309355 | 0.79 | PKM (0.80) | PKMNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL27612000 | 0.79 | TSHR (0.52) | PKMNPC1RAB9ATSHRTP53 | |
| Benzoic Acid SCHEMBL27937508 | 0.78 | PKM (0.78) | PKMNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL15022422 | 0.78 | MCL1 (0.60) | PKMNPC1RAB9ATSHRTP53 | |
| Phenol SCHEMBL27593879 | 0.78 | PKM (0.82) | PKMNPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL27290132 | 0.77 | PKM (1.00) | PKMNPC1RAB9ATSHRTP53 | |
| Toluic Acid SCHEMBL27643480 | 0.76 | PKM (0.70) | PKMNPC1RAB9ASMN1; SMN2POLB | |
| 1-Naphthol SCHEMBL28866137 | 0.76 | PKM (0.74) | PKMNPC1RAB9ASMN1; SMN2POLB | |
| Acetophenone SCHEMBL27842182 | 0.75 | PKM (0.78) | PKMNPC1RAB9ATP53SMN1; SMN2 | |
| Orthocresol SCHEMBL27371745 | 0.75 | PKM (0.78) | PKMNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1623537-A | Biaryl sulfonamides and its using method | WYETH CORP (US) | 2005-06-08 | — | — | CN | disclosed |