Thiourea

Thiourea

SCHEMBL27612166

CC(C(=O)O)N(C)C.N=C(N)S

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
SLC7A5 Q01650 1/20 0.32
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL2222199 0.85 TP53 (0.38) NOS3NOS1NOS2SLC7A5TP53
Urea SCHEMBL2033880 0.85 TP53 (0.38) NOS3NOS1NOS2SLC7A5TP53
Carbamic Acid SCHEMBL27979412 0.83 ACHE (0.37) NOS3NOS1NOS2SLC7A5TP53
Hydrazine SCHEMBL2231845 0.83 TP53 (0.40) SLC7A5TP53CHRNB2CHRNB4CHRNA3
Hydrazine SCHEMBL2231840 0.83 TP53 (0.40) SLC7A5TP53CHRNB2CHRNB4CHRNA3
SCHEMBL14889907 0.83 TP53 (0.44) SLC7A5TP53
SCHEMBL50989 0.83
SCHEMBL50988 0.83
SCHEMBL754117 0.83
SCHEMBL27445506 0.83 TP53 (0.44) SLC7A5TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105112962-A Method of preparing nickel gallium alloy by ionic liquid electrodeposition HARBIN INST OF TECHNOLOGY 2015-12-02 CN claimed
CN-105112962-A Method of preparing nickel gallium alloy by ionic liquid electrodeposition HARBIN INST OF TECHNOLOGY 2015-12-02 CN disclosed
CN-1922343-B Baths, systems and processes for electroplating zinc-nickel ternary and higher alloys and articles so electroplated ATOTECH DEUTSCHLAND GMBH (DE) 2012-02-22 CN disclosed
CN-1922343-A Baths, systems and processes for electroplating zinc-nickel ternary and higher alloys and articles so electroplated ATOTECH DEUTSCHLAND GMBH (DE) 2007-02-28 CN disclosed
CN-1759152-A Nitrogen-containing polymers for the surface treatment of metals BASF AG (DE) 2006-04-12 CN disclosed
CN-1620523-A Polymer derivatives for treating metals BASF AG (DE) 2005-05-25 CN disclosed
CN-1620485-A Polymer derivatives for the treatment of metals BASF AG (DE) 2005-05-25 CN disclosed