Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MITF | O75030 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | JAK3 | P52333 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594143 | 0.85 | MAPT (0.50) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL27612593 | 0.84 | MAPT (0.52) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL27594147 | 0.84 | MAPT (0.60) | ALDH1A1MAPTHTTRAB9AMAPK1 | |
| SCHEMBL27594145 | 0.84 | PTPN1 (0.52) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL27594135 | 0.84 | MAPT (0.59) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL5150428 | 0.84 | MAPT (0.75) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL5152995 | 0.84 | JAK3 (0.54) | ALDH1A1MAPTHTTRAB9AJAK3 | |
| SCHEMBL4003283 | 0.82 | MITF (0.72) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL27612580 | 0.81 | MAPT (0.65) | ALDH1A1MAPTMITFHTTRAB9A | |
| SCHEMBL27612563 | 0.81 | MAPT (0.51) | ALDH1A1MAPTMITFHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585756-A | Substituted diphenyl heterocycles useful for treating HCV infection | RIGEL PHARMACEUTICALS INC (US) | 2005-02-23 | — | — | CN | disclosed |