Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 9/20 | 0.49 |
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MPI | P34949 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867190 | 0.81 | DRD4 (0.53) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL2412911 | 0.78 | GAA (0.58) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL28751299 | 0.75 | MAPT (0.51) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL16867189 | 0.75 | GAA (0.44) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL16867187 | 0.75 | GAA (0.55) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL9608917 | 0.74 | DRD4 (0.55) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL6852145 | 0.74 | DRD4 (0.55) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL2408942 | 0.74 | DRD4 (0.55) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL8276924 | 0.74 | DRD4 (0.55) | GAADRD4DRD2DRD3RAB9A | |
| SCHEMBL27163243 | 0.74 | DRD4 (0.55) | GAADRD4DRD2DRD3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |