Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 8/20 | 0.55 |
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 7/20 | 0.55 |
| ▸ | HPGDS | O60760 | 1/20 | 0.53 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867187 | 0.85 | GAA (0.55) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL28980400 | 0.81 | MEN1 (0.41) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL15180418 | 0.81 | DRD4 (0.52) | GAADRD4DRD2DRD3MAPT | |
| SCHEMBL6533912 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3MAPTLMNA | |
| SCHEMBL6533713 | 0.81 | NOTUM (0.51) | GAADRD4DRD2DRD3MAPT | |
| SCHEMBL6852145 | 0.81 | DRD4 (0.55) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL9608917 | 0.81 | DRD4 (0.55) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL27163243 | 0.81 | DRD4 (0.55) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL2408942 | 0.81 | DRD4 (0.55) | GAADRD4DRD2DRD3HPGDS | |
| SCHEMBL8276924 | 0.81 | DRD4 (0.55) | GAADRD4DRD2DRD3HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2024-07-25 | — | — | US | disclosed |
| EP-4329889-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022227015-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2022-11-03 | — | — | WO | disclosed |
| WO-2022232333-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2022-11-03 | — | — | WO | disclosed |
| CN-109689644-B | Pyridazinone compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-107964007-B | Pyridazinone compound and application thereof | 沈阳中化农药化工研发有限公司 | 2021-02-12 | — | — | CN | disclosed |
| CN-109689644-A | Pyridazinone compound and its application | 沈阳中化农药化工研发有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-107964007-A | Pyridazinone compound and its application | 沈阳中化农药化工研发有限公司 | 2018-04-27 | — | — | CN | disclosed |
| US-9920075-B2 | Triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| US-9920075-B2 | Triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-03-20 | — | — | US | disclosed |
| CN-101068797-A | Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof | MITSUBISHI PHARMA CORP (JP) | 2007-11-07 | — | — | CN | disclosed |
| EP-1816128-A1 | CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |
| CN-1890241-A | A2BAdenosine receptor antagonists | CV THERAPEUTICS INC (US) | 2007-01-03 | — | — | CN | disclosed |
| US-20050119287-A1 | A2B adenosine receptor antagonists | GILEAD PALO ALTO, INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-4556409-A | CONTROLLING SOYBEAN GROWTH | EMERY INDUSTRIES INC. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4522749-A | Process for augmenting or enhancing the aroma of a fragrance by adding a vinylcyclopropane compound | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1985-06-11 | — | — | US | disclosed |
| US-4418202-A | HERBICIDES, PESTICIDES | EMERY INDUSTRIES, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| US-4380656-A | PESTICIDES, HERBICIDES | EMERY INDUSTRIES, INC. (US) | 1983-04-19 | — | — | US | disclosed |
| US-4151293-A | MITICIDES | ABBOTT LABORATORIES (US) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119287-A1 | A2B adenosine receptor antagonists | ADORA2B, ADORA2A, ADORA3 | GAA 3483/4885DRD4 691/4885DRD2 346/4885 |
| US-20240246937-A1 | IL4I1 INHIBITORS AND METHODS OF USE | IL4I1, IL4, IL2 | GAA 3303/4885DRD4 1225/4885DRD2 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.