Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 7/20 | 0.70 |
| ▸ | NOS3 | P29474 | 6/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594363 | 0.91 | NOS1 (0.63) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27554919 | 0.91 | NOS1 (0.63) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27549058 | 0.91 | NOS1 (0.66) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27594375 | 0.89 | NOS1 (0.63) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6620008 | 0.86 | NOS1 (0.74) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27612980 | 0.85 | NOS1 (0.73) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6618730 | 0.85 | NOS1 (0.76) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27471830 | 0.85 | NOS1 (0.49) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL27470928 | 0.85 | NOS1 (0.50) | NOS1NOS3CHRM2CHRM4HTR2A | |
| SCHEMBL6618161 | 0.83 | NOS1 (1.00) | NOS1NOS3CHRM2CHRM4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1617743-A | New pharmaceutical combinations for nos inhibitors | PFIZER PROD INC (US) | 2005-05-18 | — | — | CN | claimed |
| CN-1617743-A | New pharmaceutical combinations for nos inhibitors | PFIZER PROD INC (US) | 2005-05-18 | — | — | CN | disclosed |