Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612821 | 0.83 | RPS6KB2 (0.33) | RPS6KB2 | |
| SCHEMBL31716338 | 0.79 | RPS6KB2 (0.57) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27612819 | 0.78 | KDM4E (0.42) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27594239 | 0.76 | KDM4E (0.51) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27612961 | 0.76 | KDM4E (0.36) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL27613083 | 0.76 | CYP1A2 (0.42) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL6854011 | 0.73 | KDM4E (0.40) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL6854007 | 0.73 | KDM4E (0.40) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL6854014 | 0.73 | KDM4E (0.40) | KDM4ERAB9ANPC1MAPTGLA | |
| SCHEMBL31716148 | 0.72 | RPS6KB2 (0.46) | KDM4ERAB9ANPC1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |