Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612756 | 0.82 | HDAC1 (0.31) | HDAC1 | |
| SCHEMBL27613084 | 0.78 | KDM4E (0.40) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL31716338 | 0.75 | RPS6KB2 (0.57) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL27594204 | 0.75 | KDM4E (0.55) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL27612912 | 0.74 | KDM4E (0.36) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL27613086 | 0.74 | CYP1A2 (0.44) | KDM4ENPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6853984 | 0.72 | KDM4E (0.43) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL6853980 | 0.72 | KDM4E (0.43) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL4470259 | 0.70 | KDM4E (0.55) | KDM4EMAPTNPC1RAB9AGLA | |
| SCHEMBL27612839 | 0.69 | KDM4E (0.40) | KDM4EMAPTNPC1RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |