Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.69 |
| ▸ | IGF1R | P08069 | 3/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.50 |
| ▸ | GSK3A | P49840 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CDK7 | P50613 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 13/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778784 | 0.89 | SYK (0.71) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1779125 | 0.89 | SYK (0.71) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1778650 | 0.88 | SYK (0.70) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1778035 | 0.88 | SYK (0.64) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1777627 | 0.88 | SYK (0.75) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL3104144 | 0.85 | GSK3B (0.69) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1778661 | 0.85 | SYK (0.61) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL14439423 | 0.84 | SYK (0.51) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1777291 | 0.83 | SYK (0.86) | SYKIGF1RLCKGSK3AGSK3B | |
| SCHEMBL1776988 | 0.83 | SYK (0.74) | SYKIGF1RLCKGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379734-C | Azaindoles | AVENTIS PHARMA LTD (GB) | 2008-04-09 | — | — | CN | disclosed |
| CN-1615873-A | Azaindoles compound | AVENTIS PHARMA LTD (GB) | 2005-05-18 | — | — | CN | disclosed |