SCHEMBL3104144

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27709362	0.90	GSK3B (0.61)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL1777186	0.89	GSK3B (0.65)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL1777132	0.87	GSK3B (0.63)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL1777871	0.86	GSK3B (0.62)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL27613610	0.85	SYK (0.69)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL1777000	0.85	IGF1R (0.61)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL7694196	0.85	GSK3B (0.56)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL12605974	0.84	IGF1R (0.49)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL28751327	0.83	GSK3B (0.59)	GSK3BGSK3AIGF1RCDK7AURKB
	SCHEMBL27613433	0.83	GSK3B (0.59)	GSK3BGSK3AIGF1RCDK7AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.