Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613848 | 0.88 | GAA (0.45) | GAALMNAKMT2ACYP1A2CYP2D6 | |
| SCHEMBL27992803 | 0.78 | MEN1 (0.46) | LMNAKMT2AALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL27613846 | 0.77 | CYP3A4 (0.41) | GAALMNAKMT2ACYP1A2CYP2D6 | |
| SCHEMBL27613874 | 0.77 | CYP3A4 (0.41) | GAALMNAKMT2ACYP1A2CYP2D6 | |
| SCHEMBL27756525 | 0.77 | KMT2A (0.48) | KMT2APPARGPPARAEPHX2 | |
| SCHEMBL27613831 | 0.73 | CYP2D6 (0.33) | CYP2D6CA2 | |
| SCHEMBL27613842 | 0.73 | CA12 (0.35) | CYP2D6CA2 | |
| SCHEMBL9718184 | 0.71 | GAA (0.45) | GAAHSD17B10LMNAPOLBKMT2A | |
| SCHEMBL27957672 | 0.70 | CA1 (0.34) | GAAKMT2ACYP2D6CA2 | |
| SCHEMBL27904017 | 0.70 | CA1 (0.34) | GAAKMT2ACYP2D6CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1911930-A | Chemokine receptor anagonists, methods and use therefor | MILLENNIUM PHARM INC (US) | 2007-02-14 | — | — | CN | disclosed |
| CN-1585772-A | Chemokine receptor antagonists and methods and uses thereof | MILLENNIUM PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |