Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771407 | 0.84 | ITK (0.88) | ITK | |
| SCHEMBL6770253 | 0.79 | ITK (1.00) | ITK | |
| SCHEMBL6632543 | 0.77 | ITK (1.00) | ITK | |
| SCHEMBL6766640 | 0.76 | ITK (0.92) | ITK | |
| SCHEMBL6771435 | 0.74 | ITK (0.82) | ITK | |
| SCHEMBL6770839 | 0.74 | ITK (0.82) | ITK | |
| SCHEMBL6635249 | 0.68 | ITK (0.64) | ITK | |
| SCHEMBL6778057 | 0.67 | BACE1 (0.64) | ITK | |
| SCHEMBL3455670 | 0.62 | HPGD (0.70) | — | |
| SCHEMBL6772813 | 0.62 | ITK (0.69) | ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1612733-A | Benzimidazoles useful as protein kinase inhibitors | BOEHRINGER INGELHEIM PHARMA (US) | 2005-05-04 | — | — | CN | disclosed |