Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27595896 | 0.93 | FGFR1 (0.45) | HSF1ROCK2ROCK1PIM1PIM3 | |
| SCHEMBL27614606 | 0.91 | HSF1 (0.55) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL6786131 | 0.79 | HSF1 (0.55) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL27614695 | 0.78 | HSF1 (0.44) | HSF1ROCK2ROCK1PIM1PIM3 | |
| SCHEMBL6783321 | 0.73 | HSF1 (0.56) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL29695654 | 0.71 | HSF1 (0.65) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL8543804 | 0.70 | HSF1 (0.57) | HSF1ROCK2ROCK1PIM1PIM2 | |
| SCHEMBL6783318 | 0.70 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL29380539 | 0.70 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFRMKNK1 | |
| SCHEMBL29695497 | 0.70 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFRMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610667-A | 3-nitropyridine derivaives and the pharmaceutical compositions containing said derivatives | DONG WHA PHARM IND CO LTD (KR) | 2005-04-27 | — | — | CN | disclosed |