Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786813 | 0.83 | HSF1 (0.48) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL27614606 | 0.81 | HSF1 (0.55) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL27614696 | 0.79 | HSF1 (0.53) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL27595866 | 0.77 | HSF1 (0.50) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL6783321 | 0.74 | HSF1 (0.56) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL6909983 | 0.74 | HSF1 (0.51) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL27595896 | 0.72 | FGFR1 (0.45) | HSF1ROCK2ROCK1MAPTNOS1 | |
| SCHEMBL27614695 | 0.72 | HSF1 (0.44) | HSF1ROCK2ROCK1MAPTNOS1 | |
| SCHEMBL6783318 | 0.71 | HSF1 (1.00) | HSF1MKNK1ROCK2ROCK1POLB | |
| SCHEMBL29380539 | 0.71 | HSF1 (1.00) | HSF1MKNK1ROCK2ROCK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610667-A | 3-nitropyridine derivaives and the pharmaceutical compositions containing said derivatives | DONG WHA PHARM IND CO LTD (KR) | 2005-04-27 | — | — | CN | disclosed |
| US-6743795-B1 | INHIBITORS FOR HEPATITIS B AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) BECAUSE THEY INTERFERE WITH REMOVAL OF RNA STRAND FROM RNA-DNA HYBRID FORMED DURING THE REVERSE TRANSCRIPTION OF VIRAL RNA TO DNA | DONG WHA PHARM. IND. CO. LTD. (KR) | 2004-06-01 | — | — | US | disclosed |