Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL30341649 | 0.95 | MAOA (0.58) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Fluorene SCHEMBL27708363 | 0.95 | MAOA (0.58) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Fluorene SCHEMBL28233312 | 0.93 | MAOA (0.56) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Fluorene SCHEMBL28263838 | 0.88 | MAOA (0.61) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Fluorene SCHEMBL27791149 | 0.83 | MAOA (0.67) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Formic Acid SCHEMBL8436468 | 0.83 | CYP1A2 (0.52) | MAOAALDH1A1LMNAMAPTSRD5A2 | |
| Fluorene SCHEMBL27655654 | 0.81 | MAOA (0.58) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Fluorene SCHEMBL28112745 | 0.81 | MAOA (0.58) | MAOAALDH1A1KDM4ENPC1LMNA | |
| Formic Acid SCHEMBL5378796 | 0.80 | CYP1A2 (0.50) | MAOAALDH1A1MAPTSRD5A2BCHE | |
| Fluorene SCHEMBL29478468 | 0.80 | MAOA (0.68) | MAOAALDH1A1KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475816-C | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2009-04-08 | — | — | CN | disclosed |
| CN-1872857-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1872856-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | disclosed |