SCHEMBL27614907

SCHEMBL27614907

CCCCCCCCCCCCCCCCCC[SiH2][SiH3]

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
THRB P10828 1/20 0.50
DNM1 Q05193 7/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC22A1 O15245 1/20 0.38
EPHX1 P07099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8380588 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27755160 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8380482 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL6447684 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL8385766 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5870114 1.00
SCHEMBL2567996 1.00
SCHEMBL8385629 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL16793280 1.00 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9379976 0.97 TSHR (0.47) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430583-A The method for treating disease and illness using interleukin-10 阿尔莫生物科技股份有限公司 2018-08-21 CN disclosed
CN-108025040-A The method that disease and illness are treated using interleukin-10 阿尔莫生物科技股份有限公司 2018-05-11 CN disclosed
CN-106999558-A Base undecylate composition of (17 β) 3 oxygen androstane-14 alkene 17 and its production and use 来普卡公司 2017-08-01 CN disclosed
CN-105939722-A Tau peptides, anti-tau antibodies, and methods of use thereof 伊皮埃里安股份有限公司 2016-09-14 CN disclosed
CN-101405240-B Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO LTD 2012-07-25 CN disclosed
CN-101405240-A Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO LTD (JP) 2009-04-08 CN disclosed
CN-1639188-A Hepta-, octa-and nonapeptides with anti-angiogenic activity ABBOTT LAB (US) 2005-07-13 CN disclosed
CN-85105429-A The preparation desugar is the method for the carboxylates derivatives of Aaron Copland peaceful (deglucoteicoplanin) too 1987-01-14 CN disclosed