Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380588 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL27755160 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL8380482 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL8385766 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL27614907 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5870114 | 1.00 | — | — | |
| SCHEMBL2567996 | 1.00 | — | — | |
| SCHEMBL8385629 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL16793280 | 1.00 | TSHR (0.50) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL9379976 | 0.97 | TSHR (0.47) | TSHRTHRBDNM1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050100567-A1 | Liquid concentrate for the preservation of cosmetic and pharmaceutical products | AIR LIQUIDE SANTE (INTERNATIONAL) (FR) | 2005-05-12 | — | — | US | claimed |
| EP-3995320-A1 | ENERGY-EFFICIENT SOLVENT-FREE PROCESS FOR ORGANOSILANIZATION OF SILICATE AND SILICON DIOXIDE MATERIALS | Continental Reifen Deutschland GmbH (DE) | 2022-05-11 | — | — | EP | disclosed |
| US-6927244-B2 | Comprises diene-ethylene-propylene copolymer mixed with sulfur-containing/mercapto-based silane coupling agent to reduce stiffness | TOKAI RUBBER INDUSTRIES, LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| EP-1448570-A1 | PROCESS FOR PREPARING SILYLORGANOMERCAPTANS | GENERAL ELECTRIC COMPANY (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003040153-A1 | PROCESS FOR PREPARING SILYLORGANOMERCAPTANS | GENERAL ELECTRIC COMPANY (US) | 2003-05-15 | — | — | WO | disclosed |